Reduce the role microaggregates play in mediating adverse reactions to transfusions
The SQ40™ Filter’s 40 µm rated polyester screen media is process controlled and monitored to ensure uniformity of pore size to assure maximum patient protection from microaggregates, clots, and particulate debris from stored blood.
Large volume transfusions have clearly shown an association between microaggregate debris in stored blood blocking pre-capillary arterioles and the incidence of Acute Respiratory Distress Syndrome (ARDS).1,2,3 Reul demonstrated that microaggregates from stored blood were involved in the development of ARDS, and that fine screen filtration significantly improved patients’ microvasculature and clinical recovery after massive blood transfusions.
Enhanced ease-of-use
With its small filter housing, priming is rapid. The tapered spike which is compatible with all conventional blood bags permits easy insertion and transfer from one bag to another during multiple unit transfusions.
Minimal filter hold-up volume with high product recovery
Low residual blood hold-up volume (20 mL) ensures the highest recovery of blood component being transfused.
Cost-effective filter set and better inventory management
There is no need to have both standard blood and platelet administration sets. The SQ40 Filter is compatible with all blood components. This includes whole blood, packed red blood cells, platelet, and granulocyte concentrates and ViaSpan Cold Storage Solution.
Increase filter life
Media pleating and total filter area provide up to twelve times the typical first surface area of a depth-type microaggregate filter. This not only increases filter life, but also reduces the number of administration set changes required for rapid transfusion, particularly for blood components with a large debris load.
Minimize blood trauma and achieve rapid flow during massive transfusions
What determines how well blood flows through a filter? The larger the open area, the better the flow and the longer it can be maintained. With its large open area (40 cm2) and small screen thickness (60 microns), there is low sheer stress even at high flow rates. The SQ40 Filter is pressure-infuser compatible.
1 Fowler AA, Hamman RF, Good JT, Benson KN, Baird M, Eberle DJ, Petty TL, Hyers TM. Adult Respiratory Distress Syndrome: Risk with Common Predispositions. Ann Int Med 19833; 98:593-597.
2 Reul GJ, Greenberg SD, Lafrak EA, McCollum WB, Beall AC, Jordan GL. Prevention of Post-Traumatic Pulmonary Insufficiency. Arch Surg 1973; 106:386-394.
3 Reul GJ, Beall AC, Greenberg SD. Protection of the Pulmonary Microvasculature by Fine Screen Blood Filtration. Chest 1974; 66:4-9.